Which safety concern is particularly associated with cocaine use?

Cocaine use is particularly associated with the safety concern of stroke due to its effects on the cardiovascular system. Cocaine is a powerful stimulant that raises blood pressure and heart rate, which can lead to vascular damage. This increased stress on the cardiovascular system can result in blood vessels becoming constricted, and in some cases, it can cause clots to form. When a clot travels to the brain or when blood vessels in the brain are damaged, it can lead to a stroke, which is a serious medical emergency. The relationship between cocaine and stroke emphasizes the risks of its use, particularly for individuals with pre-existing health conditions or those who engage in high amounts of the substance.

The other options—chronic fatigue, hearing loss, and frequent headaches—do not have the same level of direct association with cocaine as stroke does, highlighting the unique and severe health risks tied to cocaine use.